Skeletal muscle
- Form and function
Autor(es) - Brian Maclntosh; Phillip Gardiner; Alan McComas
- €105.57 €95.00
Skeletal Muscle: Form and Function, Second Edition, provides readers with a detailed understanding of the different facets of muscle physiology. Meticulously researched and updated, this text examines motoneuron and muscle structure and function. It is intended for those who need to know about skeletal muscle—from undergraduate and graduate students gaining advanced knowledge in kinesiology to physiotherapists, physiatrists, and other professionals whose work demands understanding of muscle form and function.
A unique feature of this book is that it combines basic sciences (anatomy, physiology, biophysics, and chemistry) with clinical applications (detection of disease and genetic mutations and training and rehabilitation). Each chapter ends with a section on clinical and other applied aspects of the information presented in that chapter, showing, for example, how specific defects of muscle or nerve cells can result in certain clinical disorders. The result is a thorough understanding of skeletal muscle structure and physiology.
This new edition includes the following:
The latest research in all areas of muscle physiology
Major revisions of chapters covering muscle contraction, muscle metabolism, and fatigue
More than 200 drawings (many of them original) and 30 photos (mostly micrographs), all of which clarify and augment the text
Pedagogical aids to facilitate comprehension, including key points in the margins, special interest points, an index, and a greatly expanded glossary
Skeletal Muscle: Form and Function, Second Edition, is divided into three parts. Part I presents the structures of the neuromuscular system: muscle, motoneurons, and neuromuscular junctions and sensory receptors as well as the development of these structures. Part II examines muscle function, including neuromuscular transmission, muscle contraction, motor units, and muscle metabolism. Part III focuses on the adaptability of the neuromuscular system. Among the issues it explores are fatigue, loss and recovery of muscle innervation, trophism, muscle training, and injury and repair.
The depth and breadth of the contents, combined with the practical applications, make this book the leading authority on the structure, electrophysiology, and adaptability of human skeletal muscle. It is an excellent text for students and a practical and up-to-date reference for professionals.
ÍNDICE
Part I: Structure and Development
Chapter 1. Muscle Architecture and Muscle Fiber Anatomy
Muscle Architecture
Muscle Connective Tissue
Basement Membrane
Plasmalemma
Myofibrils
Tubular Systems
Nuclei and Mitochondria
Applied Physiology
Chapter 2. The Motoneuron
General Features of Motoneurons
Motoneuron Soma
Cytoskeletal Proteins in the Motoneuron
Axon, Dendrites, and Glia
Applied Physiology
Chapter 3. The Neuromuscular Junction
General Features of the Neuromuscular Junction
Muscle Fiber Acetylcholine Receptors
The Basement Membrane at the Neuromuscular Junction
Axon Terminal
Applied Physiology
Chapter 4. Muscle Receptors
The Muscle Spindle
The Golgi Tendon Organ
Free Nerve Endings
Role of Muscle Receptors During Locomotor Activity
Applied Physiology
Chapter 5. Muscle Formation
Step 1: Mesoderm Is Induced from Ectoderm
Step 2: A Portion of Mesoderm Forms Somites, Then Develops Into Skeletal Muscle
Step 3: The Myogenic (Muscle Forming) Cells Proliferate and Then Differentiate
Step 4: The Body Plan Is Laid Down
Step 5: Muscles Are Assembled
Postnatal Development of Muscle
Applied Physiology
Chapter 6. Development of Muscle Innervation
Step 1: Inductive Signals Pass From Mesoderm to Ectoderm
Step 2: The Neural Tube Forms From Thickening and Invagination of the Dorsal Ectoderm
Step 3: Nerve Cells Proliferate and Then Migrate
Step 4: Axons Grow Out From the Spinal Cord Along the Extracellular Matrix
Step 5: The Axons Establish Connections With the Muscle Fibers
Step 6: Redundant Synapses and Motoneurons Are Eliminated
Applied Physiology
Part II: Putting Muscles to Work
Chapter 7. Ion Channels, Pumps, and Binding Proteins
General Properties of Channels and Pumps
Sodium Channels
The Sodium Pump (Na+-K+ Pump)
Potassium Channels
Calcium Channels and Pumps
Calcium-Binding Proteins
Calcium Pumps
Anion Channels
Applied Physiology
Chapter 8. Axoplasmic Transport
Confirmation and Categorization of Axoplasmic Transport
Applied Physiology
Chapter 9. Resting and Action Potentials
Resting Membrane Potential
The Action Potential
Applied Physiology
Chapter 10. Neuromuscular Transmission
Acetylcholine Release
Postsynaptic Events
Applied Physiology
Chapter 11. Muscle Contraction
Sliding Filament Theory of Muscle Contraction
The Cross-Bridge Theory of Skeletal Muscle
The Key Contractile Proteins: Myosin and Actin
Excitation-Contraction Coupling
The Contractile Response
The Length Dependence of Force
Dynamic Contractions
Applied Physiology
Chapter 12. Motor Units
Organization of Motor Units
Physiological and Biochemical Properties of Motor Units
Classification of Motor Units
Applied Physiology
Chapter 13. Motor Unit Recruitment
Detection of Motor Unit Activation
The Size Principle
Maximal Voluntary Contraction
Applied Physiology
Chapter 14. Muscle Metabolism
Energy Required for Muscle Contraction
Replacing Adenosine Triphosphate
Integration of the Metabolic Systems
Regulation of the Metabolic Systems
How Much Energy Is Needed?
Applied Physiology
Part III: The Adaptable Neuromuscular System
Chapter 15. Fatigue
Defining Fatigue
Central Fatigue
Peripheral Fatigue
Excitation-Contraction Coupling Failure
Biochemical Changes in Muscle Fibers
Recovery From Fatigue
Applied Physiology
Chapter 16. Loss of Muscle Innervation
Changes in Motor Axons and Neuromuscular Junctions
Changes in Muscle Fibers
Applied Physiology
Chapter 17. Recovery of Muscle Innervation
Nerve Regeneration
Collateral Reinnervation
Changes in the Muscle Fibers Following Reinnervation
Motor Unit Properties Following Reinnervation
Applied Physiology
Chapter 18. Trophism
Motoneuron Effects on Muscle
Muscle Effects on Motoneurons
Applied Physiology
Chapter 19. Disuse
Studies in Human Subjects
Studies in Animals
Applied Physiology
Chapter 20. Muscle Training
Muscle Strength and Power
Human Endurance Training
Training Studies in Animals
Adaptive Changes in DNA and RNA Processing
Applied Physiology
Chapter 21. Injury and Repair
Muscle Contraction-Induced Damage
Muscle Injury From External Causes
Applied Physiology
Chapter 22. Aging
Changes in Muscle With Aging
Motoneuron Changes in Aging
Changes in Axons and Neuromuscular Junctions
Applied Physiology
- Formato: Capa dura
- Nº de páginas: 423
- Editado em: 2006
- Idioma: Inglês
- ISBN: 9780736045179